The AVENIO Tumor Tissue Surveillance Kit V2 is an NGS research assay that complements the AVENIO ctDNA Surveillance Kit V2 designed for longitudinal monitoring of tumor burden, by establishing a baseline from formalin-fixed paraffin-embedded (FFPE) tissue samples. This assay contains 17 genes in U.S. National Comprehensive Cancer Network (NCCN)2 and other guidelines, as well as an additional 180 genes that are used for tumor burden monitoring and MRD detection in lung cancer and colorectal cancer.
Features and Benefits
- Panel content exactly-matched to gene panel in the AVENIO ctDNA Surveillance Kit (same genes, gene regions and hybrid-capture workflow) to facilitate the establishment of a baseline for longitudinal tumor burden monitoring and for concordance analysis between tissue and plasma
- All four mutation classes (SNVs, indels, fusions and CNVs) in a single DNA workflow
- Flexibility to switch between tissue and plasma to support a variety of research applications
- A streamlined, end-to-end research workflow from extraction to analysis and reporting in 5 days
- A complete research solution that includes reagents, intuitive analysis and reporting to facilitate in-house adoption of high performance NGS oncology testing
Specifications
- Panel size: 198 kb
- Sample size: 2×10 µm FFPET sections/curls
- DNA input*: 20 ng of amplifiable DNA
- Reactions per kit: 24
- Turn-around time: 5 days from extraction to results
* Total DNA amount for each sample was determined by input QC.
Contents
| Box # | Sub-kit name |
|---|---|
| 1 | AVENIO Tumor DNA Isolation and QC Kit |
| 2 | AVENIO Tumor Cleanup and Capture BeadsV2 |
| 3 | AVENIO Tumor Library Prep Kit V2 |
| 4 | AVENIO Tumor Sample Primers – Plate A or Plate B |
| 5 | AVENIO Tumor Enrichment Kit V2 |
| 6 | AVENIO Tumor Tissue Surveillance Panel V2 |
| 7 | AVENIO Post-Hybridization Kit V2 |
Exceptional Performance2
References
- National Comprehensive Cancer Network. Accessed Aug 2, 2023.
- Data on file with Roche.
